Tom Hamer makes his first start in over four months after returning from injury.
The defender needed surgery after being forced off against Northampton Town in October. Hamer is one of five players brought into the starting XI by head coach Michael Skubala.
George Wickens starts in goal, with Reeco Hackett, James Collins and Jovon Makama also elevated to the starting XI.
Makama - who caught the eye in his goalscoring cameo off the bench on Saturday - wants he and his team-mates to take the impressive display from the final 30 minutes or so at Oakwell into tonight’s match.
Bailey Cadamarteri is fit to be included on the bench for the first time since mid January after returning from injury.
Skubala said: “The front three were really exciting when they came on at Barnsley so they’ve earned the right to go again.
“It’s about replicating that now from the start - they showed the quality and intensity that we want to see, and we want to start tonight like we finished on Saturday.
“We want to start fast, and our best performances here have come from us doing that. But even if we don’t get the quick goal we want we want to keep pushing the game.”
Imps: Wickens, Darikwa, Jackson, Hackett, Bayliss, McGrandles, Jefferies, Hamer, Roughan, Collins, Makama.
Substitutes: Jeacock, Cadamarteri, Hamilton, House, Clucas, Gardner, Draper.
Crawley: Wollacott, Feely, Conroy, Baker, Anderson, Swan, Quitirna, Adeyemo, Doyle, Radcliffe, John-Jules.
Substitutes: Sheik, Forster, Holohan, Tanimu, Padadopoulos, Watson.
