Head coach Michael Skubala makes one change to the side that defeated Doncaster Rovers at the LNER Stadium last Saturday.
Ben House comes into the starting XI, with Freddie Draper making way. Reeco Hackett returns to the bench after recovering from an injury setback.
Skubala said: "Wycombe are a good team who are hard to beat, especially at home, and have won seven of their past 10 games after Michael Duff came in. There's no doubt they are in a false position and they will be up there come the end of the season.
"They keep going until the end so we know we'll have to be on it, in terms of performance and physicality, right until the final whistle.
"There are not many changes with us bringing in House as the only one to the starting XI, but we think we have a team that can go and get something from the game."
Jack Moylan is also in the squad, after making his injury comeback as a second half substitute in the recent Vertu Trophy victory against Barnsley.
Imps: Wickens, Darikwa, Reach, Bayliss, Collins, McGrandles, Bradley, Street, House, Okoronkwo, Hamer.
Subs: Jeacock, Towler, Hackett, Moylan, Obikwu, Varfolomeev, Draper.
