City head coach Michael Skubala makes four changes from last Saturday’s fixture at Wycombe Wanderers.
Freddie Draper and Justin Obikwu have both been rewarded for their scoring contributions at Adams Park, replacing James Collins and Rob Street.
Jack Moylan comes in for his first league start since the trip to AFC Wimbledon in August, having recovered from injury, with Reeco Hackett also handed a start. They come in place of Tom Bayliss and Frankie Okoronkwo.
Skubala said: "I thought Jack was fantastic last week when he came off the bench.
"We wanted to go aggressive and get two strikers on the pitch and again, I thought Justin and Freddie made a real impact last weekend. It is an attacking line-up, we want to go after the game and be positive at home."
Imps: Wickens, Darikwa, Reach, Hackett, Moylan, McGrandles, Bradley, House, Obikwu, Hamer, Draper.
Subs: Jeacock, Towler, Bayliss, Collins, Ring, Street, Varfolomeev.